Stay Current
Publications, milestones, awards, and updates from the Deppmann Lab.
Godschall, Gungul, Sajonia et al. publish in Nature, identifying a central amygdala circuit through which next-generation GLP-1 weight-loss drugs suppress hedonic feeding, separate from the pathway that controls hunger. Co-led by the Deppmann and Guler labs at UVA.
Read in Nature →Katya Stepanova and Jiachen Shi have successfully defended their PhD dissertations in Biology! Katya's research uncovered the role of Schwann cells in axon degeneration after nerve injury, and Jiachen's work revealed cell death programs that shape the brain from development to degeneration using single-cell and imaging mass cytometry. Both will remain in the lab through the spring as they prepare for their next chapters. Congratulations to our newest doctors!
Meet the team →Godschall et al. publish a preprint revealing how next-generation weight-loss drugs (GLP-1/GIP receptor agonists) inhibit brain reward circuits, providing new mechanistic insight into how these drugs affect feeding behavior.
View publication →A comprehensive developing mouse brain atlas using single-cell mass cytometry (CyTOF) is published, providing an unprecedented high-dimensional view of brain cell diversity.
View publication →Shi et al. publish new findings on extrinsic apoptosis mechanisms, expanding our understanding of how cells execute programmed death through external signals.
View publication →Sarah Hunter-Chang successfully defends her PhD dissertation in Neuroscience and pursues entrepreneurship, launching a biotech startup.
View alumni network →The lab receives a new R01 grant (co-PI with Bruce Carter at Vanderbilt) totaling $2.6M for 2024–2029, investigating how long-distance regressive signaling sculpts the nervous system during development.
Mehrael Atkins, Cheng Yang, and Jingxuan Guo join the Deppmann Lab as new PhD students, bringing fresh perspectives to our research on neural circuits and metabolism.
Meet the team →Amy Van Deusen successfully defends her PhD dissertation in Neuroscience after seven years of research in the lab studying neural circuit development.
View alumni network →Kumar, Kahle, Keeler, Zunder, and Deppmann publish new methods for characterizing microglial signaling dynamics during inflammation using single-cell mass cytometry.
View publication →Multiple Deppmann Lab members present posters and talks at the annual Society for Neuroscience meeting, showcasing work on axon degeneration, brain metabolism, and sensory neuroscience.
On the Air
Podcast appearances and media features by Chris Deppmann.
Chris Deppmann featured on the Nature Podcast, in conversation about the mechanism by which acute stress drives loss of melanocyte stem cells — and how that explains why hair turns grey.
Chris Deppmann will appear on an upcoming episode of The Pain Beat Podcast. Check back for the episode link and air date.
Follow the Deppmann Lab for the latest research breakthroughs, student accomplishments, and opportunities to collaborate.